Información del producto
BACE1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP, IHC
Target
BACE1
Research Area
Neuroscience, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:1000
Type Clonality
polyclonal
Immunogen
beta-site APP-cleaving enzyme 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Beta-secretase 1|Aspartyl protease 2 (ASP2, Asp 2)|Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1)|Memapsin-2|Membrane-associated aspartic protease 2|BACE1|BACE|KIAA1149
Host
Rabbit
UniProt ID
P56817
Gene ID
23621
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
70-75 kDa
Background
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP,