Información del producto
APEX1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP, IF
Target
APEX1
Research Area
Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
APEX nuclease (multifunctional DNA repair enzyme) 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
DNA-(apurinic or apyrimidinic site) endonuclease|APEX nuclease (APEN)|Apurinic-apyrimidinic endonuclease 1 (AP endonuclease 1, APE-1)|REF-1|Redox factor-1|DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial|APEX1|APE|APE1|APEX|APX|HAP1|REF1
Host
Rabbit
UniProt ID
P27695
Gene ID
328
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
39 kDa
Background
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so