Información del producto
ADAM17-Specific antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
ADAM17
Research Area
Signal Transduction, Metabolism, Cardiovascular, Immunology, Developmental biology, Neuroscience
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
ADAM metallopeptidase domain 17
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17)|Snake venom-like protease|TNF-alpha convertase|TNF-alpha-converting enzyme|ADAM17|CSVP|TACE
Host
Rabbit
UniProt ID
P78536
Gene ID
6868
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
29 kDa
Background
The ADAMs(A Disintegrin And Metalloprotease) are multidomain transmembrane proteins. One of the first ADAMs implicated in membrane shedding is ADAM-17, which is shown to release the active form of tumor necrosis factor(TNF)-a from its precursor(PMID:18238