Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
AATF
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
apoptosis antagonizing transcription factor
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Protein AATF|Apoptosis-antagonizing transcription factor|Rb-binding protein Che-1|AATF|CHE1|DED
Host
Rabbit
UniProt ID
Q9NY61
Gene ID
26574
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
63 kDa
Background
May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 fr