Storage ConditionsPBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
ApplicationsFC
TargetRat CD45
Formliquid
Recomended DilutionEach lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should ti
Type ClonalityMonoclonal
SynonymsLCALy-5T200| Leukocyte common antigen| Ptprc| Receptor-type tyrosine-protein phosphatase C
CategoriaFlow cytometry Antibodies
HostMouse
UniProt IDP04157
Gene ID19265
Iso typeIgG1, κ
ReactivityRat
ConjugationAPC
BackgroundCD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all he
isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. Th