Storage ConditionsPBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
ApplicationsFC
TargetMouse CD170
Formliquid
Recomended DilutionVolume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Plea
Type ClonalityMonoclonal
SynonymsOBBP2|CD33L2|OB-BP2
CategoriaFlow cytometry Antibodies
HostRat
UniProt IDQ920G3
Gene ID8778
Iso typeIgG1, κ
ReactivityMouse
ConjugationPE-Cy7
BackgroundCD170, also known as Siglec-F, Siglec-5, is a member of the Sialic acid-binding Ig-like lectin family, type I single pass transmembrane protein, with 4 extracellular Ig-like domains and 2 ITIM motifs in the cytoplasmic domain
preferentially binds [alpha]-2,3-linked sialic acid. Siglec F is expressed in eosinophils, alveolar macrophages and intestinal microfold (M) cells and induces apoptosis of the lung eosinophils during allergic asthma.