Información del producto
APC Anti-Human CD195/CCR5 Antibody(HEK/1/85a)
Información adicional
Size
100T
Storage Conditions
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
FC
Target
Human CD195/CCR5
Form
liquid
Recomended Dilution
Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Plea
Type Clonality
Monoclonal
Synonyms
CCR5|C-C chemokine receptor type 5|HIV-1 fusion co-receptor
Categoria
Flow cytometry Antibodies
Host
Mouse
UniProt ID
P51681
Gene ID
1234
Iso type
IgG2a, κ
Reactivity
Human
Conjugation
APC
Background
CD195, also known as CCR5, is a 45 kD G protein-coupled seven transmembrane CC-chemokine receptor. It binds to MIP-1α, MIP-1β, and RANTES and is expressed on a subset of T cells and monocytes. CD195 mediates an intracellular signal thought to induce cell
modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.
modification of CCR5 by sulfation contributes to the efficiency of HIV-1 entry. Recent studies have shown CCR5 to play a role in a variety of other human diseases, ranging from infectious and inflammatory diseases to cancer.