Información del producto
PE-Cy5.5 Anti-Human CD197/CCR7 Antibody(FN437H)
Información adicional
Size
20T
Storage Conditions
PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
FC
Target
Human CD197/CCR7
Form
liquid
Recomended Dilution
Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Plea
Type Clonality
Monoclonal
Synonyms
EBI1EVI1|CCR-7|CDw197|CMKBR7
Categoria
Flow cytometry Antibodies
Host
Mouse
UniProt ID
P32248
Gene ID
1236
Iso type
IgG2a, κ
Reactivity
Human
Conjugation
PE-Cy5.5
Background
CCR7, also known as CD197, is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity by affecting interactions between T cells and dendritic cells and their downstream effect. Naïve T cells enter the lymph
this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.
this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated with lymph node metastasis.