Información del producto
BRCA2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
BRCA2
Research Area
Epigenetics, Cancer, Metabolism
Form
liquid
Recomended Dilution
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
breast cancer 2, early onset
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Breast cancer type 2 susceptibility protein|Fanconi anemia group D1 protein|BRCA2|FACD|FANCD1
Host
Rabbit
UniProt ID
P51587
Gene ID
675
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
384 kDa
Background
Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA(ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabl
together with PALB2 is involved in both POLH localization at collapsed replication forks and DNA polymerization activity. In concert with NPM1, regulates centrosome duplication. Interacts with the TREX-2 complex(transcription and export complex 2) subunit
together with PALB2 is involved in both POLH localization at collapsed replication forks and DNA polymerization activity. In concert with NPM1, regulates centrosome duplication. Interacts with the TREX-2 complex(transcription and export complex 2) subunit