Información del producto
SIRT1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
SIRT1
Research Area
Neuroscience, Stem Cells, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:10 - 1:100
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
sirtuin (silent mating type information regulation 2 homolog) 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
NAD-dependent protein deacetylase sirtuin-1 (hSIRT1)|NAD-dependent protein deacylase sirtuin-1|Regulatory protein SIR2 homolog 1|SIR2-like protein 1 (hSIR2)|SirtT1 75 kDa fragment (75SirT1)|SIRT1|SIR2L1
Host
Rabbit
UniProt ID
Q96EB6
Gene ID
23411
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
130 kDa
Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been det
however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The pr
however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The pr