Información del producto
ZW10 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
ZW10
Research Area
Cell Division and Proliferation, Developmental biology
Form
liquid
Recomended Dilution
IP: 1:200-1:2000
WB: 1:500-1:5000
WB: 1:500-1:5000
Type Clonality
polyclonal
Immunogen
ZW10, kinetochore associated, homolog(Drosophila)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Centromere/kinetochore protein zw10 homolog|ZW10
Host
Rabbit
UniProt ID
O43264
Gene ID
9183
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
90 kDa
Background
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is pro
the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).
the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241).