Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
ZBTB38
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
WB: 1:500-1:5000
Type Clonality
polyclonal
Immunogen
zinc finger and BTB domain containing 38
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Zinc finger and BTB domain-containing protein 38|ZBTB38
Host
Rabbit
UniProt ID
Q8NAP3
Gene ID
253461
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
134 kDa
Background
Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single met
represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons(By similarity).