Información del producto
VPS35 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF, IP
Target
VPS35
Research Area
Neuroscience
Form
liquid
Recomended Dilution
IF: 1:10-1:100
IP: 1:200-1:1000
WB: 1:200-1:1000
IP: 1:200-1:1000
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
vacuolar protein sorting 35 homolog
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Vacuolar protein sorting-associated protein 35 (hVPS35)|Maternal-embryonic 3|Vesicle protein sorting 35|VPS35|MEM3
Host
Rabbit
UniProt ID
Q96QK1
Gene ID
55737
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
92 kDa
Background
Acts as component of the retromer cargo-selective complex(CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lyso
however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosom
however, these interactions seem to be of low affinity and retromer SNX proteins may also contribute to cargo selectivity thus questioning the classical function of the CSC. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosom