Información del producto
TNNC1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
TNNC1
Research Area
Neuroscience, Cardiovascular, Developmental biology, Signal Transduction
Form
liquid
Recomended Dilution
IF: 1:50 - 1:200
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
troponin C type 1 (slow)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Troponin C, slow skeletal and cardiac muscles (TN-C)|TNNC1|TNNC
Host
Rabbit
UniProt ID
P63316
Gene ID
7134
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
18 kDa
Background
TnT, which contains the binding site for tropomyosin
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associate
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase
and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associate