Información del producto
TNIP1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF, IP
Target
TNIP1
Research Area
Immunology, Metabolism
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
TNFAIP3 interacting protein 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
TNFAIP3-interacting protein 1|A20-binding inhibitor of NF-kappa-B activation 1 (ABIN-1)|HIV-1 Nef-interacting protein|Nef-associated factor 1 (Naf1)|Nip40-1|Virion-associated nuclear shuttling protein (VAN, hVAN)|TNIP1|KIAA0113|NAF1
Host
Rabbit
UniProt ID
Q15025
Gene ID
10318
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
72 kDa
Background
Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B-dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG
blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in
proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway
this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation
this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear loc
blocks MAPK3/MAPK1 nuclear translocation and MAPK1-dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in
proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway
this function implicates binding to polyubiquitin. Involved in leukocyte integrin activation during inflammation
this function is mediated by association with SELPLG and dependent on phosphorylation by SRC-family kinases. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear loc