Información del producto
TNFSF13B antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
TNFSF13B
Research Area
Immunology, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
tumor necrosis factor(ligand) superfamily, member 13b
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Tumor necrosis factor ligand superfamily member 13B|B lymphocyte stimulator (BLyS)|B-cell-activating factor|BAFF|Dendritic cell-derived TNF-like molecule|TNF- and APOL-related leukocyte expressed ligand 1 (TALL-1)|Tumor necrosis factor ligand superfamily
Host
Rabbit
UniProt ID
Q9Y275
Gene ID
10673
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
32 kDa, 45-52 kDa
Background
Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands-2 receptors pathway involved in the stimulation of B-and T-cell function and the regulation of humoral immunity. A third
Isoform 2 seems to inhibit isoform 1 secretion and bioactivity.
Isoform 3: Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-sti
Isoform 2 seems to inhibit isoform 1 secretion and bioactivity.
Isoform 3: Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-sti