Información del producto
TERF2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
TERF2
Research Area
Cell Division and Proliferation, Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
telomeric repeat binding factor 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Telomeric repeat-binding factor 2|TTAGGG repeat-binding factor 2|Telomeric DNA-binding protein|TERF2|TRBF2|TRF2
Host
Rabbit
UniProt ID
Q15554
Gene ID
7014
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
65-69 kDa
Background
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and en
without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Together with DCLRE1B/Apollo, plays a key role in telomeric loop(T loop) formation b
without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Together with DCLRE1B/Apollo, plays a key role in telomeric loop(T loop) formation b