Información del producto
TBC1D5 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
TBC1D5
Research Area
Cancer
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2400
IP: 1:200-1:1000
WB: 1:500-1:2400
Type Clonality
polyclonal
Immunogen
TBC1 domain family, member 5
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
TBC1 domain family member 5|TBC1D5|KIAA0210
Host
Rabbit
UniProt ID
Q92609
Gene ID
9779
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
89 kDa
Background
May act as a GTPase-activating protein(GAP) for Rab family protein(s). May act as a GAP for RAB7A. Can displace RAB7A and retromer CSC subcomplex from the endosomal membrane to the cytosol
at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN)
the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy in
at least retromer displacement seems to require its catalytic activity(PubMed:19531583, PubMed:20923837). Required for retrograde transport of cargo proteins from endosomes to the trans-Golgi network(TGN)
the function seems to require its catalytic activity. Involved in regulation of autophagy(PubMed:22354992). May act as a molecular switch between endosomal and autophagosomal transport and is involved in reprogramming vesicle trafficking upon autophagy in