Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
SPTLC1
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
serine palmitoyltransferase, long chain base subunit 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Serine palmitoyltransferase 1|Long chain base biosynthesis protein 1 (LCB 1)|Serine-palmitoyl-CoA transferase 1 (SPT 1, SPT1)|SPTLC1|LCB1
Host
Rabbit
UniProt ID
O15269
Gene ID
10558
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
53 kDa
Background
-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of th
This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxo