Información del producto
SIAH1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
SIAH1
Research Area
Neuroscience, Epigenetics, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:50 - 1:200
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
seven in absentia homolog 1 (Drosophila)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
E3 ubiquitin-protein ligase SIAH1|RING-type E3 ubiquitin transferase SIAH1|Seven in absentia homolog 1 (Siah-1)|Siah-1a|SIAH1|HUMSIAH
Host
Rabbit
UniProt ID
Q8IUQ4
Gene ID
6477
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
31 kDa
Background
This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has
s disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
s disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.