Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
PREB
Research Area
Metabolism
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
prolactin regulatory element binding
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Prolactin regulatory element-binding protein|Mammalian guanine nucleotide exchange factor mSec12|PREB|SEC12
Host
Rabbit
UniProt ID
Q9HCU5
Gene ID
10113
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
45 kDa
Background
Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport ves
Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene(PRL) promoter and seems to activate transcription.