Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
PKM1
Research Area
Stem Cells, Cancer, Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
IHC: 1:100-1:400
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
peptide
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
PKM1|PK-M1|PKM1 pyruvate kinase|muscle|PKM|Pyruvate kinase PKM
Host
Rabbit
UniProt ID
P14618
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
58 kDa
Background
PKM, also named as OIP3, PK2, PK3, PKM, p58, THBP1, CTHBP and Tumor M2-PK, belongs to the pyruvate kinase family. It is glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate(PEP) to ADP, generating ATP. It stimulates
however, the primary isoform from four independent tumours is PK-M2(PMID:18337823). This antibody is specific to PKM1 isoform.