Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
PARN
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:50 - 1:200
WB: 1:1000 - 1:3000
Type Clonality
polyclonal
Immunogen
poly(A)-specific ribonuclease (deadenylation nuclease)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Poly(A)-specific ribonuclease PARN|Deadenylating nuclease|Deadenylation nuclease|Polyadenylate-specific ribonuclease|PARN|DAN
Host
Rabbit
UniProt ID
O95453
Gene ID
5073
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
90 kDa
Background
-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of
-exoribonuclease, with similarity to the RNase D family of 3&apos
The protein encoded by this gene is a 3&apos