Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
PACSIN1
Research Area
Neuroscience, Signal Transduction, Metabolism
Form
liquid
Recomended Dilution
IF: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
protein kinase C and casein kinase substrate in neurons 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Protein kinase C and casein kinase substrate in neurons protein 1|Syndapin-1|PACSIN1|KIAA1379
Host
Rabbit
UniProt ID
Q9BY11
Gene ID
29993
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
48-51 kDa
Background
Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT
this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neu
this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission(By similarity). Binds to membranes via its F-BAR domain and mediates memb