Información del producto
POU5F1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
POU5F1
Research Area
Cancer, Immunology, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:50 - 1:200
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
POU class 5 homeobox 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
POU domain, class 5, transcription factor 1|Octamer-binding protein 3 (Oct-3)|Octamer-binding protein 4 (Oct-4)|Octamer-binding transcription factor 3 (OTF-3)|POU5F1|OCT3|OCT4|OTF3
Host
Rabbit
UniProt ID
Q01860
Gene ID
5460
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
50 kDa
Background
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate
s sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human po
s sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human po