Información del producto
NIT1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
NIT1
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
WB: 1:500-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
nitrilase 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Deaminated glutathione amidase (dGSH amidase)|Nitrilase homolog 1|NIT1
Host
Rabbit
UniProt ID
Q86X76
Gene ID
4817
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
36 kDa
Background
Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells
this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2(By similarity).
this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2(By similarity).