Información del producto
MMP14 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
MMP14
Research Area
Cancer, Cardiovascular, Metabolism, Signal Transduction
Form
liquid
Recomended Dilution
IHC: 1:50 - 1:100
WB: 1:500 - 1:2000
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
matrix metallopeptidase 14 (membrane-inserted)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Matrix metalloproteinase-14 (MMP-14)|MMP-X1|Membrane-type matrix metalloproteinase 1 (MT-MMP 1, MTMMP1)|Membrane-type-1 matrix metalloproteinase (MT1-MMP, MT1MMP)|MMP14
Host
Rabbit
UniProt ID
P50281
Gene ID
4323
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
65 kDa
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art
each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily
each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily