Información del producto
LAS1L antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
LAS1L
Research Area
Cell Division and Proliferation
Form
liquid
Recomended Dilution
IP: 1:200-1:2000
WB: 1:500-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
LAS1-like
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Ribosomal biogenesis protein LAS1L|Endoribonuclease LAS1L|Protein LAS1 homolog|LAS1L
Host
Rabbit
UniProt ID
Q9Y4W2
Gene ID
81887
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
83 kDa, 70-75 kDa
Background
Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP(5FMC) complex
the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.