Información del producto
KANK2 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
KANK2
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
IF: 1:20-1:200
WB: 1:500-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
KN motif and ankyrin repeat domains 2
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
KN motif and ankyrin repeat domain-containing protein 2|Ankyrin repeat domain-containing protein 25|Matrix-remodeling-associated protein 3|SRC-1-interacting protein (SIP, SRC-interacting protein, SRC1-interacting protein)|KANK2|ANKRD25|KIAA1518|MXRA3|SIP
Host
Rabbit
UniProt ID
Q63ZY3
Gene ID
25959
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
95 kDa
Background
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm
proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity).
the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation
proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus(PubMed:22371500). May be involved in promotion of cell proliferation(By similarity).
the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway(PubMed:24671081). May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation