Información del producto
KANK1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IF, IHC, WB
Target
KANK1
Research Area
Signal Transduction
Form
liquid
Recomended Dilution
IF: 1:20-1:200
IHC: 1:20-1:200
WB: 1:500-1:2000
IHC: 1:20-1:200
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
KN motif and ankyrin repeat domains 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
KN motif and ankyrin repeat domain-containing protein 1|Ankyrin repeat domain-containing protein 15|Kidney ankyrin repeat-containing protein|KANK1|ANKRD15|KANK|KIAA0172
Host
Rabbit
UniProt ID
Q14678
Gene ID
23189
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
150 kDa
Background
Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity
the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia
the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of tr
the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading
the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia
the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of tr
the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading