Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
IRF1
Research Area
Epigenetics, Cancer, Immunology, Metabolism
Form
liquid
Recomended Dilution
IF: 1:50 - 1:100
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
interferon regulatory factor 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Interferon regulatory factor 1 (IRF-1)|IRF1
Host
Rabbit
UniProt ID
P10914
Gene ID
3659
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
45-50 kDa
Background
DNA damage responses and DNA repair, such as POLQ/POLH
MHC class I expression, such as TAP1, PSMB9/LMP2, PSME1/PA28A, PSME2/PA28B and B2M and MHC class II expression, such as CIITA. Represses genes involved in anti-proliferative response, such as BIRC5/survivin, CCNB1, CCNE1, CDK1, CDK2 and CDK4 and in immune
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. These include the regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expr
anti-proliferative response, such as p53/TP53, LOX and CDKN1A
antibacterial response, such as NOS2/INOS
apoptosis, such as BBC3/PUMA, CASP1, CASP7 and CASP8
immune response, such as IL7, IL12A/B and IL15, PTGS2/COX2 and CYBB