Información del producto
GPX4 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
GPX4
Research Area
Metabolism
Form
liquid
Recomended Dilution
IF: 1:50 - 1:200
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
glutathione peroxidase 4 (phospholipid hydroperoxidase)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Phospholipid hydroperoxide glutathione peroxidase GPX4 (PHGPx)|Glutathione peroxidase 4 (GPx-4, GSHPx-4)|GPX4
Host
Rabbit
UniProt ID
P36969
Gene ID
2879
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
22 kDa
Background
The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozy
UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variant
moonlighting&apos
protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a sele
thus, it has been identified as a &apos
UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variant
moonlighting&apos
protein because of its ability to serve dual functions as a peroxidase, as well as a structural protein in mature spermatozoa. Mutations in this gene are associated with Sedaghatian type of spondylometaphyseal dysplasia (SMDS). This isozyme is also a sele
thus, it has been identified as a &apos