Información del producto
FBP1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB, IF, IP
Target
FBP1
Research Area
Metabolism
Form
liquid
Recomended Dilution
IF: 1:50-1:500
IHC: 1:100-1:400
IP: 1:500-1:1000
WB: 1:5000-1:20000
IHC: 1:100-1:400
IP: 1:500-1:1000
WB: 1:5000-1:20000
Type Clonality
polyclonal
Immunogen
fructose-1,6-bisphosphatase 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Fructose-1,6-bisphosphatase 1 (FBPase 1)|D-fructose-1,6-bisphosphate 1-phosphohydrolase 1|Liver FBPase|FBP1|FBP
Host
Rabbit
UniProt ID
P09467
Gene ID
2203
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
37 kDa
Background
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cel
increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.