Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IF
Target
ELAC2
Research Area
Cancer, Metabolism, Developmental biology
Form
liquid
Recomended Dilution
IF: 1:50 - 1:100
IHC: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
elaC homolog 2 (E. coli)
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Zinc phosphodiesterase ELAC protein 2|ElaC homolog protein 2|Heredity prostate cancer protein 2|Ribonuclease Z 2 (RNase Z 2)|tRNA 3 endonuclease 2|tRNase Z 2|ELAC2|HPC2
Host
Rabbit
UniProt ID
Q9BQ52
Gene ID
60528
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
105 kDa
Background
#8242
The protein encoded by this gene has a C-terminal domain with tRNA 3&
processing endoribonuclease activity, which catalyzes the removal of the 3&apos
trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest.