Información del producto
DOCK7 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP
Target
DOCK7
Research Area
Neuroscience, Developmental biology
Form
liquid
Recomended Dilution
IP: 1:500-1:1000
WB: 1:200-1:1000
WB: 1:200-1:1000
Type Clonality
polyclonal
Immunogen
dedicator of cytokinesis 7
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Dedicator of cytokinesis protein 7|DOCK7|KIAA1771
Host
Rabbit
UniProt ID
Q96N67
Gene ID
85440
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
240 kDa
Background
Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and con
negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody ca
negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3(By similarity).Multiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody ca