Información del producto
DHX36 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC, IP
Target
DHX36
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
IP: 1:200-1:1000
WB: 1:500-1:2000
IP: 1:200-1:1000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
DEAH(Asp-Glu-Ala-His) box polypeptide 36
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
ATP-dependent DNA/RNA helicase DHX36|DEAD/H box polypeptide 36|DEAH-box protein 36|G4-resolvase-1 (G4R1)|MLE-like protein 1|RNA helicase associated with AU-rich element protein|DHX36|DDX36|KIAA1488|MLEL1|RHAU
Host
Rabbit
UniProt ID
Q9H2U1
Gene ID
170506
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
120 kDa
Background
Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived fr
the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR
the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR