Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
CD22
Research Area
Stem Cells, Immunology, Signal Transduction, Cancer
Form
liquid
Recomended Dilution
IHC : 1:500-1:2000
WB : 1:1000-1:10000
Type Clonality
monoclonal
Immunogen
CD22 molecule
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
B-cell receptor CD22|B-lymphocyte cell adhesion molecule (BL-CAM)|Sialic acid-binding Ig-like lectin 2 (Siglec-2)|T-cell surface antigen Leu-14|CD22|SIGLEC2
Host
Mouse
UniProt ID
P20273
Gene ID
933
Purification
Protein A+G purification
Clone Number
7D10
Iso type
IgG1
Reactivity
Human
Observed MW
135 kDa
Background
Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins
one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response