Información del producto
CD209 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
CD209
Research Area
Neuroscience, Immunology, Signal Transduction
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
CD209 molecule
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
CD209 antigen|C-type lectin domain family 4 member L|Dendritic cell-specific ICAM-3-grabbing non-integrin 1 (DC-SIGN, DC-SIGN1)|CD209|CLEC4L
Host
Rabbit
UniProt ID
Q9NNX6
Gene ID
30835
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
45 kDa
Background
(Microbial infection) Acts as an attachment receptor for HIV-1 and HIV-2(PubMed:11799126, PubMed:12502850, PubMed:1518869). Acts as an attachment receptor for ebolavirus(PubMed:12502850, PubMed:12504546). Acts as an attachment receptor for cytomegalovirus
On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to reg
Pathogen-recognition receptor expressed on the surface of immature dendritic cells(DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The r
On DCs it is a high affinity receptor for ICAM2 and ICAM3 by binding to mannose-like carbohydrates. May act as a DC rolling receptor that mediates transendothelial migration of DC presursors from blood to tissues by binding endothelial ICAM2. Seems to reg
Pathogen-recognition receptor expressed on the surface of immature dendritic cells(DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The r