Información del producto
CBFA2T3 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB
Target
CBFA2T3
Research Area
Metabolism
Form
liquid
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
core-binding factor, runt domain, alpha subunit 2
translocated to, 3
translocated to, 3
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Protein CBFA2T3|MTG8-related protein 2|Myeloid translocation gene on chromosome 16 protein (hMTG16)|Zinc finger MYND domain-containing protein 4|CBFA2T3|MTG16|MTGR2|ZMYND4
Host
Rabbit
UniProt ID
O75081
Gene ID
863
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
62-65 kDa
Background
Isoform 2 functions as an A-kinase-anchoring protein(PubMed:11823486).
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expr
interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway(PubMed:25974097). Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the exp
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expr
interacts with EGLN1 and promotes the HIF1A prolyl hydroxylation-dependent ubiquitination and proteasomal degradation pathway(PubMed:25974097). Contributes to inhibition of glycolysis and stimulation of mitochondrial respiration by down-regulating the exp