Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, IF, WB
Target
Bcl-XL
Research Area
Neuroscience, Cancer, Immunology, Cardiovascular
Form
liquid
Recomended Dilution
IF: 1:50-1:500
IHC: 1:50-1:500
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
BCL2-like 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Bcl-2-like protein 1 (Bcl2-L-1)|Apoptosis regulator Bcl-X|BCL2L1|BCL2L|BCLX
Host
Rabbit
UniProt ID
Q07817
Gene ID
598
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat
Observed MW
30 kDa
Background
Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mi
Isoform Bcl-X(S) promotes apoptosis.
Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel(VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membra