Información del producto
APEX1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IP, IF
Target
APEX1
Research Area
Cardiovascular, Metabolism
Form
liquid
Recomended Dilution
IF: 1:50 - 1:100
IP: 1:50 - 1:200
WB: 1:500 - 1:2000
IP: 1:50 - 1:200
WB: 1:500 - 1:2000
Type Clonality
polyclonal
Immunogen
APEX nuclease (multifunctional DNA repair enzyme) 1
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
DNA-(apurinic or apyrimidinic site) endonuclease|APEX nuclease (APEN)|Apurinic-apyrimidinic endonuclease 1 (AP endonuclease 1, APE-1)|REF-1|Redox factor-1|DNA-(apurinic or apyrimidinic site) endonuclease, mitochondrial|APEX1|APE|APE1|APEX|APX|HAP1|REF1
Host
Rabbit
UniProt ID
P27695
Gene ID
328
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
39 kDa
Background
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so
all encode the same protein.
to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene
all encode the same protein.
to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene