Información del producto
ALCAM antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, IHC, WB
Target
ALCAM
Research Area
Stem Cells, Immunology, Signal Transduction, Developmental biology
Form
liquid
Recomended Dilution
IHC: 1:20-1:200
WB: 1:200-1:2000
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
activated leukocyte cell adhesion molecule
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
CD166 antigen|Activated leukocyte cell adhesion molecule|ALCAM|MEMD
Host
Rabbit
UniProt ID
Q13740
Gene ID
214
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
110 kDa
Background
Cell adhesion molecule that mediates both heterotypic cell-cell contacts via its interaction with CD6, as well as homotypic cell-cell contacts(PubMed:7760007, PubMed:15496415, PubMed:15048703, PubMed:16352806, PubMed:23169771, PubMed:24945728). Promotes T
Isoform 3: Inhibits activities of membrane-bound isoforms by competing for the same interaction partners. Inhibits cell attachment via homotypic interactions. Promotes endothelial cell migration. Inhibits endothelial cell tube formation.
axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons(By similarity).
required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation(By similarity). Promotes neurite extension, axon growth and axon guidance
Isoform 3: Inhibits activities of membrane-bound isoforms by competing for the same interaction partners. Inhibits cell attachment via homotypic interactions. Promotes endothelial cell migration. Inhibits endothelial cell tube formation.
axons grow preferentially on surfaces that contain ALCAM. Mediates outgrowth and pathfinding for retinal ganglion cell axons(By similarity).
required for normal numbers of hematopoietic stem cells in bone marrow. Promotes in vitro osteoblast proliferation and differentiation(By similarity). Promotes neurite extension, axon growth and axon guidance