Información del producto
AKAP8L antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IF
Target
AKAP8L
Research Area
Cell Division and Proliferation
Form
liquid
Recomended Dilution
IF: 1:20-200
WB: 1:200-1:2000
WB: 1:200-1:2000
Type Clonality
polyclonal
Immunogen
A kinase(PRKA) anchor protein 8-like
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
A-kinase anchor protein 8-like (AKAP8-like protein)|Helicase A-binding protein 95 (HAP95)|Homologous to AKAP95 protein (HA95)|Neighbor of A-kinase-anchoring protein 95 (Neighbor of AKAP95)|AKAP8L|NAKAP|NAKAP95
Host
Rabbit
UniProt ID
Q9ULX6
Gene ID
26993
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human
Observed MW
72 kDa
Background
(Microbial infection) In case of EBV infection, may target PRKACA to EBNA-LP-containing nuclear sites to modulate transcription from specific promoters(PubMed:11884601). Can synergize with DHX9 to activate the CTE-mediated gene expression of type D retrov
Could play a role in constitutive transport element(CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export(PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem
in this function seems to act redundantly with AKAP8(PubMed:16980585). May be involved in regulation of pre-mRNA splicing(PubMed:17594903).
in vitro negatively regulates DHX9 annealing activity(PubMed:25034436).
Could play a role in constitutive transport element(CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export(PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem
in this function seems to act redundantly with AKAP8(PubMed:16980585). May be involved in regulation of pre-mRNA splicing(PubMed:17594903).
in vitro negatively regulates DHX9 annealing activity(PubMed:25034436).