Información del producto
AIRE antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
AIRE
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:20-200
WB: 1:500-1:5000
WB: 1:500-1:5000
Type Clonality
polyclonal
Immunogen
autoimmune regulator
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Autoimmune regulator|Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein (APECED protein)|AIRE|APECED
Host
Rabbit
UniProt ID
O43918
Gene ID
326
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse
Observed MW
60 kDa
Background
Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment
the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes(By similarity). Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3'
the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes(By similarity). Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3'