Información del producto
YY1 antibody
Información adicional
Size
100µg
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Applications
ELISA, WB, IHC
Target
YY1
Research Area
Metabolism
Form
liquid
Recomended Dilution
IHC: 1:50-1:500
WB: 1:500-1:2000
WB: 1:500-1:2000
Type Clonality
polyclonal
Immunogen
YY1 transcription factor
Minimum Purity
≥95% as determined by SDS-PAGE
Synonyms
Transcriptional repressor protein YY1|Delta transcription factor|INO80 complex subunit S|NF-E1|Yin and yang 1 (YY-1)|YY1|INO80S
Categoria
loading control
Host
Rabbit
UniProt ID
P25490
Gene ID
7528
Purification
Immunogen affinity purified
Iso type
IgG
Reactivity
Human, Mouse, Rat, Rabbit, pig, monkey, zebrafish, hamster
Observed MW
60 kDa, 75 kDa
Background
Multifunctional transcription factor that exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. Binds to the consensus sequence 5'-CCGCCATNTT-3'
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair
proposed to target the INO80 complex to YY1-responsive elements.
some genes have been shown to contain a longer binding motif allowing enhanced binding
the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair
proposed to target the INO80 complex to YY1-responsive elements.
some genes have been shown to contain a longer binding motif allowing enhanced binding
the initial CG dinucleotide can be methylated greatly reducing the binding affinity. The effect on transcription regulation is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect