Storage Conditions
-20°C/1 year
Applications
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
Type Clonality
Polyclonal
Immunogen
Recombinant Protein of ATG4b
Subcellular Location
Cytoplasm . Cytoplasm, cytosol . Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum . Mitochondrion . Mainly localizes to the cytoplasm, including cytosol (PubMed:29165041). A samll potion localizes to mitochondria
phosphorylation at Ser-34 promotes localization to mitochondria (PubMed:29165041). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
23192
Observed Band
44kD
Other Name
AUT-like 1 cysteine endopeptidase
Autophagin-1
Autophagy-related cysteine endopeptidase 1
Autophagy-related protein 4 homolog B
Cysteine protease ATG4B (EC 3.4.22.-
hAPG4B)
Background
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, a