Storage Conditions
-20°C/1 year
Applications
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC 1:100-200
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of CLIC1 AA range: 166-216
Subcellular Location
Nucleus . Nucleus membrane
Single-pass membrane protein . Cytoplasm . Cell membrane
Single-pass membrane protein . Mostly in the nucleus including in the nuclear membrane (PubMed:9139710, PubMed:12681486). Small amount in the cytoplasm and the plasma membrane (PubMed:9139710). Exists both as soluble cytoplasmic protein and as membrane pr
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1192
Observed Band
30kD
Other Name
Chloride intracellular channel protein 1 (Chloride channel ABP
NCC27
Nuclear chloride ion channel 27
Regulatory nuclear chloride ion channel protein
hRNCC)
Background
chloride intracellular channel 1(CLIC1) Homo sapiens Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellu
the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008],