Storage Conditions
-20°C/1 year
Applications
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:1000-2000, IHC 1:100-200
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of CXCR4 AA range: 203-253
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell junction. Early endosome. Late endosome. Lysosome. In unstimulated cells, diffuse pattern on plasma membrane. On agonist stimulation, colocalizes with ITCH at the plasma membrane where it becomes ubiquitinated. In the pr
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7852
Observed Band
50kD
Other Name
C-X-C chemokine receptor type 4
CD antigen CD184
CXC-R4
CXCR-4
CXCR4
FB22
Fusin
HM89
LCR1
LESTR
Leukocyte-derived seven transmembrane domain receptor
NPYRL
SDF-1 receptor
Stromal cell-derived factor 1 receptor
Background
C-X-C motif chemokine receptor 4(CXCR4) Homo sapiens This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to supp