Storage Conditions
-20°C/1 year
Applications
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC 1:100-200
Type Clonality
Polyclonal
Immunogen
Synthetic Peptide of Endothelin B Receptor AA range: 270-350
Subcellular Location
Cell membrane
Multi-pass membrane protein. internalized after activation by endothelins. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1910
Observed Band
50kD
Other Name
ET-BR
Endothelin B receptor (ET-B
Endothelin receptor non-selective type)
Background
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest t