Información del producto
Estrogen Receptor α rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
WB
Concentration
1 mg/ml
Recomended Dilution
WB: 1:500-1:2000
Type Clonality
Polyclonal
Immunogen
Recombinant Protein of Estrogen Receptor α
Subcellular Location
Cytoplasmic side . A minor fraction is associated with the inner membrane.
Cytoplasmic side. Cell membrane
Nucleus. Golgi apparatus. Cell membrane. Colocalizes with ZDHHC7 and ZDHHC21 in the Golgi apparatus where most probably palmitoylation occurs. Associated with the plasma membrane when palmitoylated.
Peripheral membrane protein
Peripheral membrane protein
Single-pass type I membrane protein. Associated with the inner membrane via palmitoylation (Probable). At least a subset exists as a transmembrane protein with a N-terminal extracellular domain. .
[Isoform 1]: Nucleus . Cytoplasm . Cell membrane
[Isoform 3]: Nucleus. Cytoplasm. Cell membrane
Cytoplasmic side. Cell membrane
Nucleus. Golgi apparatus. Cell membrane. Colocalizes with ZDHHC7 and ZDHHC21 in the Golgi apparatus where most probably palmitoylation occurs. Associated with the plasma membrane when palmitoylated.
Peripheral membrane protein
Peripheral membrane protein
Single-pass type I membrane protein. Associated with the inner membrane via palmitoylation (Probable). At least a subset exists as a transmembrane protein with a N-terminal extracellular domain. .
[Isoform 1]: Nucleus . Cytoplasm . Cell membrane
[Isoform 3]: Nucleus. Cytoplasm. Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2099
Observed Band
66kD
Other Name
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Background
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or